Iron Withdrawal Halts Hepatitis

"Hepatitis from oral iron substitution"

Clin Rheumatol. 2000;19(3):222-5.  Links
Acute hepatitis in adult Still's disease apparently resulting from
oral iron substitution--a case re****t.
Maclachlan D, Tyndall A.
University Department of Rheumatology, Basel, Switzerland.
maclach...@[EMAIL PROTECTED]
 authors re****t a case of a young woman with adult-onset Still's
disease (AOSD) with massive hyperferritinaemia who developed acute
florid hepatitis with intraparenchymatous histiocytic infiltration
following oral iron substitution for presumed iron deficiency, which
settled on withdrawal of the iron.
This suggests that the iron exacerbated the macrophage hyperactivity
which is presumed to be present in AOSD.
Oral iron substitution in the acute phase of this disease may be
inadvisable.


PMID: 10870659


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