Re: Tolerance to pain meds

Wow!  Great quesion!  I hope somebody has some insight on this one.  I've 
had multiple painful surgeries in the past year and a half and have
noticed 
the same thing that Marie stated.

I remember when 1/2 fioricet knocked me for a loop.  Now, after taking 
vicodin, percocet, etc. for joint replacements in my big toes and my knee
--  
the migraine seems to need quite a bit more to knock it out.  I can't 
believe I can take 2 fioricet and hardly feel it.  I've been tempted to
take 
1/2 more but the rebound I get isn't worth it.

Anybody got an answer to this?  Teri?  Sandy?

Liz

"Lagomorpheus" <plutonium@[EMAIL PROTECTED]
> wrote in message 
news:ed86ea73-931b-4ef6-b082-bdea1de9a4ac@[EMAIL PROTECTED]
> Hello,
> I have noticed over the years that the usefulness of my rescue meds
> has worn off and the dosage has had to be increased.
>
> I can remember about 10 years ago when I had my wisdom teeth out and
> one Percocet knocking me out cold. Although I take maybe one pain pill
> (a Lortab 10/500) every two weeks for a migraine, the same kind of
> "wisdom teeth" dose helps a bit with the pain, but certainly does not
> knock me out anymore.
>
> I could understand if I was taking these meds daily or on a regular
> basis, but it seems s****adic enough that they should still be
> effective.
>
> Does anyone know what is happening chemistry-wise with the body to
> make the medicine less effective over time?
>
> Is there a period from which I should completely refrain from taking
> it so that I could get back to a lower dose that would still have a
> painkilling effect?
>
> Marie