> > Gastrointestinal dysfunction is an im****tant risk factor for
> > diseases of the sebaceous glands and is correlated with
> > their occurrence and development.
>
> Could be just coincidence, but dioxin effects sebaceous glands, ie
> causes chlorance. Dioxin affects areas that are high in fat, ie
> breasts, adipose, nervous system, sebaceous glands, glands that
> produce ear wax, etc. Dioxin also suppresses the immune system and
> causes hyperinflammation in some organs (ie liver, breast) and various
> linings including endothelial lining of vascular system. Dioxin could
> very easily produce IBD by damaging the thymus, embedding itself in
> the vascular and nerves of the gut. Since dioxin continually
> recirculates in bile, the bile duct and terminal ileum would likely
> suffer damage.
I think you're inclined to filter everything through the lens of dioxin.
The simple fact is the body tries to get rid of toxins. First it tries
to send them out the G.I. tract or through the kidneys. If that doesn't
work, it tries to put the toxins on slow-growing hairs to move them out
that way and if all else fails, the body can stick it in fat cells or
bone for long-term storage where it will do the least harm. Of course,
you also have specific issues with specific toxins like dioxin but I'm
trying to think generally about how the body's detox system is tied up
in all this.
I would point to a nexus of factors like cathelicidin, HIF-1a and
metallothionein at work in the sebaceous glands. It's been shown that
in common acne you've got defective innate antimicrobial production and
it's not too many jumps down a few pathways from there until you get to
MT.
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