On Nov 17, 5:27=A0pm, ironjustice <teamtan...@[EMAIL PROTECTED]
> wrote:
> On Oct 31, 9:35=A0am, ironjustice <teamtan...@[EMAIL PROTECTED]
> wrote:
> =A0"Blackpepper, piperine, can reduce high-fat diet induced oxidative
> =A0stress" <<
>
> (NaturalNews)
> Substance in Black Pepper Increases Nutrient Absorption up to Two
> Thousand Percent
> Monday, November 17, 2008 by: Barbara L. Minton
>
> Putting black pepper on your food may be one of the easiest, most
> economical ways to boost your overall health status. Piperine, the
> main alkaloid from black pepper has been shown to substantially
> increase the bioavailability of the nutrients in foods and
> supplements. As the quality of food declines and the costs of food and
> supplements continue to skyrocket, it is increasingly im****tant to
> your health that the nutrients you consume are able to be used to
> maximum efficiency by your body.
>
> What is piperine?
>
> Piperine is a pungent compound found in the fruit of the plants in the
> Piperaceae family, the most famous member of which is Piper nigrum,
> black pepper. It has a long history of use in Ayurvedic medicine as a
> restorative and treatment.
>
> Piperine is able to increase bioavilability of many substances through
> a number of mechanisms. It inhibits several enzymes responsible for
> metabolizing nutritional substances, stimulates amino-acid
> trans****ters in the intestinal lining, inhibits removal of substances
> from cells so they continue to be available for use, and decreases the
> intestinal activity allowing more of the substances to enter the body
> in active form. The results of these actions are that substances
> reach, enter and remain within their target cells for longer periods
> of time than would normally be the case.
>
> Piperine can turn a marginally effective therapeutic substance into a
> highly effective one by increasing its bioavailability and
> intracellular residency time. As an example, piperine can increase the
> bioavailability of the cancer, inflammation and infection fighter,
> cur***in, by twenty-fold.
>
> Piperine favorably simulates the digestive enzymes of the pancreas,
> enhances digestive capacity and significantly reduces gastrointestinal
> food transit time. Black pepper or piperine treatment has also been
> evidenced to lower lipid peroxidation in vivo and beneficially
> influence the cellular status of organic sulfur compounds, antioxidant
> molecules, and antioxidant enzymes in a number of experimental
> situations of oxidative stress.
>
> In addition to its effects on bioavilability, piperine has many other
> actions in the body that include increasing beta-endorphins in the
> brain, acting as an anti-depressant, increasing s*****onin production,
> boosting brain functioning, stimulating adrenal production, relieving
> pain and asthma symptoms, stimulating melanin production, decreasing
> ulcerations of the stomach, reducing stomach acid production, and
> coordinating digestive tract contractions. It is highly effective
> against colon cancer.
>
> New research is do***enting the many health benefits of piperine
>
> The journal Biometals re****ts a study involving cadmium, a well known
> environmental carcinogen and immuno-toxicant that is characterized by
> marked atrophy of the thymus and spleen enlargement. Cadmium induces
> death in lymphocytes and alters immune functions. Researchers tested
> the ameliorative effects to cadmium damage using piperine, picroliv-
> glycosides, and cur***in polyphenols. They found that of the three
> herbals, piperine displayed maximum efficacy. All the examined doses
> of piperine increased cell viability in a dose dependent manner.
> Restoration of cell damage such as cytotoxicity, oxidative stress and
> phosphatidylserine externalization was potentiated with piperine. T
> and B cell phenotypes and cytokine release were also mitigated best
> with piperine, rendering piperine the compound of choice under immuno-
> compromised conditions.
>
> In a study re****ted in the September edition of the journal Food and
> Chemical Toxicology the effect of various doses of piperine was
> determined. Results showed that piperine at all dosage ranges used in
> the study possessed anti-depression like activity and cognitive
> enhancing effects at all treatment durations. Researchers determined
> that piperine is a functional food that improves brain functioning.
>
> The medicinal properties of various compounds such as cur***in cannot
> be well utilized because of poor bioavailability due to its rapid
> metabolism in the liver and intestinal wall. In an older study
> re****ted in Planta Medica, the effect of combining piperine, a known
> inhibitor of hepatic and intestinal glucuronidation, was evaluated to
> determine the bioavailability of cur***in in rats and healthy human
> volunteers. When cur***in was given alone to the rats, moderate serum
> concentrations were achieved over a period of 4 hours. When piperine
> was added with the cur***in, the serum concentration of cur***in
> increased for a 1-2 hour period. Time to maximum concentration was
> significantly increased while elimination half life and clearance
> significantly decreased. The bioavailability was increased by 154%.
> When cur***in was given alone to humans, serum levels were either
> undetectable or very low. Addition of piperine produced much higher
> concentrations from 0.25 to 1 hour following administration. The
> bioavailability of cur***in when taken with piperine increased 2000%.
>
> A study re****ted in the September issue of Phychopharmacology was
> designed to investigate the involvement of monoaminergic systems in
> the antidepressant activity of cur***in and the effect of piperine as
> a bioenhancer to the biological effects of cur***in. The researchers
> found that the enhanced cur***in dose dependently inhibited the
> immobility period, increased s*****onin, and inhibited the monoamine
> oxidase enzymes. The compound also enhanced the anti-immobility effect
> of sub-threshold doses of various antidepressant drugs like
> fluoxetine, venlafaxine, or bupropion. The combination of sub-
> threshold dose of enhanced cur***in and various antidepressant drugs
> resulted in synergistic increase in s*****onin levels. The co-
> administration of piperine with cur***in resulted in potentiation of
> pharmacological, biochemical, and neurochemical activities. They
> concluded that the cur***in, piperine combination proved to be a
> useful and potent natural antidepressant.
>
> The summer issue of Clinical Laboratory Science re****ts a study to
> determine if resveratrol from red grapes, cinnamaldehyde from
> cinnamon, and piperine from black pepper have anti-proliferative
> effects on colon cancer. Quantitative effects of each phytochemical on
> concentration responses and time courses of proliferation of cultured
> human colon cancer cells were *****sed. The results showed the
> phytochemicals each displayed anti-proliferative effects. Piperine
> displayed a trend toward anti-proliferation at 24 hours and
> statistically significant inhibition at 48 and 72 hours. Researchers
> concluded that all three compounds offer significant anti-
> proliferative effects on human colon cancer cells and provide
> protective effects against colon cancer.
>
> Using piperine
>
> Piperine is generally consumed as a component of black pepper. Adding
> black pepper to cooked foods, raw foods, and fresh juices is a good
> way to increase nutrient absorption. Black pepper spices up almost all
> foods, even snacks like popcorn. It can be added to the Budwig
> protocol used as a preventative and cure for cancer. It is natural
> that the foods and the compound that makes their nutrients so highly
> available go so well together.
>
> For those with an aversion to black pepper, piperine can be bought as
> a supplement called Bioperine. Source Naturals Bioperine is available
> at Lucky Vitamin. Swanson Vitamin sells a house brand of Bioperine.
> There are multi-vitamins on the market that contain Bioperine as well
> as Cur***in supplements with Bioperine added. Supplemental piperine
> should be taken along with meals and supplements for maximum benefit.
>
> Additional sources:
>
> "Piperine Re****t", Cochran Foundation of Medical Research.
>
> Russell Mills, "Piperine Multiplies the Strength of Many Supplements
> and Drugs", The Delano Re****t.
>
> About the author
> Barbara is a school psychologist, a published author in the area of
> personal finance, a breast cancer survivor using "alternative"
> treatments, a born existentialist, and a student of nature and all
> things natural.
>
> Who loves ya.
> Tom
>
> Jesus Was A Vegetarian!http://tinyurl.com/634q5a
>
> Man Is A Herbivore!http://tinyurl.com/4rq595
>
> DEAD PEOPLE WALKINGhttp://tinyurl.com/zk9fk
Resveratrol can help you to lead a long and healthy life so says Dr.
Oz.
Red wine alone does not supply enough resveratrol to achieve the
full range of benefits because one glass of red wine has only about
1mg of resveratrol and you need about 250mg/day. You need to take
high potency resveratrol supplements to achieve the results
do***ented
in scientific studies.Resveratrol Supplements can also help you
control
your weight naturally by increasing energy, reducing cravings, and
limiting
your appetite.According to Wikipedia, Consumer Lab, an independent
dietary
supplement and over the counter products evaluation organization,
published a re****t on 13 November 2007 on the popular resveratrol
supplements. The organization re****ted that there exists a wide
range
in quality, dose, and price among the 13 resveratrol products
evaluated. The actual amount of resveratrol contained in the
different brands range from 2.2mg for Revatrol, which claimed to
have
400mg of "Red Wine Grape Complex", to 500mg for Biotivia.com
Transmax,
which is consistent with the amount claimed on the product's label.
Prices per 100mg of resveratrol ranged from less than $.30 for
products made by Biotivia.com, jarrow, and country life, to a high
of
$45.27 for the Revatrol brand.
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