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Support > Crohns - Colitis > Re: Entocort vs...
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Re: Entocort vs. Humira

by "Mark Mandell" <msmandl@[EMAIL PROTECTED] > Jun 3, 2008 at 08:47 PM

"Vanny" <Vannyss2003@[EMAIL PROTECTED]
> wrote in message 
news:g1todu$eje$1@[EMAIL PROTECTED]
>I have been on Entocort (aka Budesonide) since June 2005 with a break 
>between Nov. 2005 and August 2006. I have read somewhere that 3 mg
Entocort 
>is equivalent to approximately 10 mg Prednisolone with respect to
efficacy. 
>Because my liver is rebelling (due to Opium, 6-MP, PPIs, Entocort, etc.)
I 
>have reduced the Entocort to 3 mg every alternate day with the hope of 
>coming off it sometime because the longterm side-effects are the same as 
>Prednisolone - it just takes longer to get there. I did start on 9 mg,
but 
>had too many side-effects and was OK on 6 mg for a year or so.
>
> Oral Entocort is effective against mild to moderate Crohns located in
the 
> small intestine and ascending colon and is marketed as such. 
> http://www.entocortec.com/HCP/Indications_First.asp
>
> If you have Crohn's in the tranverse and/or desdending colon and/or 
> rectum, then an Entocort enema or foam is necessary. If you have severe
or 
> fulminant Crohn's then it is unlikely that Entocort will help you. Doses

> higher than 9 mg per day have not been found to result in increased 
> efficacy. 
>
http://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?id=2616&type=display
>
> It sounds Humira as though it would be your best bet. In my experience, 
> one should respond to Entocort within 4-7 days of taking it so you have 
> given it a good shot and it was wise to move on.
>
> Side-effects and drug interactions can be found here www.drugs.com  and 
> www.rxlist.com
>
> Vanny
>
> "Mark Mandell" <msmandl@[EMAIL PROTECTED]
> schrieb im Newsbeitrag 
> news:LiV%j.3361$Q57.2204@[EMAIL PROTECTED]
>> Curious about whether Entocort(Budesonide) users have found it
effective 
>> against Crohn's flareups.
>>
>> I ask because I haven't found it quite as effective as Prednisone so
I'm 
>> considering changing to Humira.  However,  in "defense" of the Entocort
I 
>> will say I haven't taken it all that long.  I started in January and
then 
>> after two weeks changed to Prednisone(since there was no
improvement)and 
>> for five days now, have been on a combined 10 mg. Pred and 9 mg. of the

>> Entocort(I returned to the Entocort on my doctor's recommendation since

>> it doesn't have as many side effects as the Pred).
>>
>> Appreciate any feedback.
>>
>> Mark Mandell

I'm consulting my GI specialist next week and by then will know for sure 
about remaining on the Combined Entocort and Prednisone I've been recently

on.(9 mg. of the Entocort with 10 mg. of the Pred).  Inflammation may be 
under control so that the discomfort I have is from post inflammatory scar

tissue which neither Humira nor Remicade can eliminate.

Thanks for input thus far.
 




 5 Posts in Topic:
Entocort vs. Humira
"Mark Mandell"   2008-05-30 08:45:52 
Re: Entocort vs. Humira
Jeffrey Fried <jcfried  2008-05-31 16:40:50 
Re: Entocort vs. Humira
"Vanny" <Van  2008-06-01 10:58:52 
Re: Entocort vs. Humira
"Mark Mandell"   2008-06-03 20:47:27 
Re: Entocort vs. Humira
"Vanny" <Van  2008-06-04 10:50:59 

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tan12V112 Tue Dec 2 7:15:12 CST 2008.