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Support > Crohns - Colitis > Re: Entocort vs...
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Re: Entocort vs. Humira

by "Vanny" <Vannyss2003@[EMAIL PROTECTED] > Jun 1, 2008 at 10:58 AM

I have been on Entocort (aka Budesonide) since June 2005 with a break 
between Nov. 2005 and August 2006. I have read somewhere that 3 mg
Entocort 
is equivalent to approximately 10 mg Prednisolone with respect to
efficacy. 
Because my liver is rebelling (due to Opium, 6-MP, PPIs, Entocort, etc.) I

have reduced the Entocort to 3 mg every alternate day with the hope of 
coming off it sometime because the longterm side-effects are the same as 
Prednisolone - it just takes longer to get there. I did start on 9 mg, but

had too many side-effects and was OK on 6 mg for a year or so.

Oral Entocort is effective against mild to moderate Crohns located in the 
small intestine and ascending colon and is marketed as such. 
http://www.entocortec.com/HCP/Indications_First.asp

If you have Crohn's in the tranverse and/or desdending colon and/or
rectum, 
then an Entocort enema or foam is necessary. If you have severe or
fulminant 
Crohn's then it is unlikely that Entocort will help you. Doses higher than
9 
mg per day have not been found to result in increased efficacy. 
http://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?id=2616&type=display

It sounds Humira as though it would be your best bet. In my experience,
one 
should respond to Entocort within 4-7 days of taking it so you have given
it 
a good shot and it was wise to move on.

Side-effects and drug interactions can be found here www.drugs.com  and 
www.rxlist.com

Vanny

"Mark Mandell" <msmandl@[EMAIL PROTECTED]
> schrieb im Newsbeitrag 
news:LiV%j.3361$Q57.2204@[EMAIL PROTECTED]
> Curious about whether Entocort(Budesonide) users have found it effective

> against Crohn's flareups.
>
> I ask because I haven't found it quite as effective as Prednisone so I'm

> considering changing to Humira.  However,  in "defense" of the Entocort
I 
> will say I haven't taken it all that long.  I started in January and
then 
> after two weeks changed to Prednisone(since there was no improvement)and

> for five days now, have been on a combined 10 mg. Pred and 9 mg. of the 
> Entocort(I returned to the Entocort on my doctor's recommendation since
it 
> doesn't have as many side effects as the Pred).
>
> Appreciate any feedback.
>
> Mark Mandell
>
 




 5 Posts in Topic:
Entocort vs. Humira
"Mark Mandell"   2008-05-30 08:45:52 
Re: Entocort vs. Humira
Jeffrey Fried <jcfried  2008-05-31 16:40:50 
Re: Entocort vs. Humira
"Vanny" <Van  2008-06-01 10:58:52 
Re: Entocort vs. Humira
"Mark Mandell"   2008-06-03 20:47:27 
Re: Entocort vs. Humira
"Vanny" <Van  2008-06-04 10:50:59 

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tan12V112 Tue Dec 2 7:58:00 CST 2008.