Thanks to Pam Dowd for sending us the following from the evidentiary
files of breast implant litigation.
CAB100170380
Study No. 420-1171
Interim Pathology Re****t
Histopathology _ VC-II and T-IV groups
As detailed in the attached individual animal re****ts, the primary
effect of the test article was limited to the lung. All of the T-IV
rats regardless of *** had a moderate to very severe chronic
alveolar/interstitial consolidative lesion usually diffuse in
distribution. Elements of this lesion suggested an active process;
namely the occurrence of alveolar foam cells, a protein rich alveolar
transudate, and an interstitial edema with prominent interstitial
macrophages.
Generally lesions present in the VC-II rats and the tissues other than
the lung of the T-IV rats were typical of spontaneous and expected
lesions of this species and strain at this age. These lesions were not
compound related.
Signed: Stephen V. Becker DVM 5-11-83
TOXIGENICS
A Subsidiary of Whittaker Cor****ation
